34646 DEFICIENCY OF NOVEL ADIPOKINE TETRANECTIN INCREASES OBESITY AND INSULIN RESISTANCE IN FEMALES
نویسندگان
چکیده
منابع مشابه
The Effect of Short Term Aerobic Training on Serum Insulin and Insulin Resistance in Adult Obese Females
Objective: Obesity is associated with inflammatory process and many different diseases. The objective of this study was to assess the impact of short term aerobic training on serum resistin and insulin resistance in adult obese women. Materials and Methods: In this quasi-experimental study, thirty untrained adult obese females matched for age 35-45 years old with body mass index (BMI) 30-36 kg...
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OBJECTIVE We examined the relationship between the expression of thrombospondin (TSP)1, an antiangiogenic factor and regulator of transforming growth factor-beta activity, obesity, adipose inflammation, and insulin resistance. RESEARCH DESIGN AND METHODS TSP1 gene expression was quantified in subcutaneous adipose tissue (SAT) of 86 nondiabetic subjects covering a wide range of BMI and insulin...
متن کاملThe adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance.
OBJECTIVE We identified lipocalin 2 (Lcn2) as a gene induced by dexamethasone and tumor necrosis factor-alpha in cultured adipocytes. The purpose of this study was to determine how expression of Lcn2 is regulated in fat cells and to ascertain whether Lcn2 could be involved in metabolic dysregulation associated with obesity. RESEARCH DESIGN AND METHODS We examined Lcn2 expression in murine tis...
متن کاملPrevalence of Obesity, Dyslipidemia, and Insulin Resistance in Childhood Cancer Survivors
Background: With the increased survival rates following the treatment of childhood cancer, it becomes equally important that the need for evidence based surveillance of long term effects of cancer therapy is addressed. This includes the risk of development of metabolic syndrome features like obesity, altered lipid and sugar profile, which was attempted in the present study. Materials and Metho...
متن کاملCD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice.
CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and triglyceride (TG) levels and decreased glucose levels. Studies in spontaneous hypertensive rats lacking functional CD36 link CD36 to the insulin-resistance syndrome. To clarify the relationship between CD36 and insulin sensitivity in more detail...
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ژورنال
عنوان ژورنال: Journal of Clinical and Translational Science
سال: 2021
ISSN: 2059-8661
DOI: 10.1017/cts.2021.453